GAMBARAN PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN RAWAT JALAN DI RSUD H.M. RYACUDU KOTABUMI LAMPUNG UTARA TAHUN 2025

Zhafran, M. Rafi (2026) GAMBARAN PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN RAWAT JALAN DI RSUD H.M. RYACUDU KOTABUMI LAMPUNG UTARA TAHUN 2025. Diploma thesis, POLTEKKES KEMENKES PALEMBANG.

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Abstract

ABSTRAK
Latar Belakang : Hipertensi merupakan penyakit tidak menular yang ditandai dengan peningkatan tekanan darah dan menjadi salah satu penyebab utama penyakit kardiovaskular. Penggunaan obat antihipertensi yang tepat berperan penting dalam mengendalikan tekanan darah serta mencegah terjadinya komplikasi. Penelitian ini bertujuan untuk mengetahui gambaran penggunaan obat antihipertensi pada pasien rawat jalan di RSUD H.M. Ryacudu Kotabumi Lampung Utara Tahun 2025 serta menilai kesesuaian terapi berdasarkan pedoman JNC 8.
Metode : Penelitian ini menggunakan metode non-eksperimental dengan desain deskriptif. Sampel penelitian sebanyak 499 rekam medis dan resep pasien hipertensi rawat jalan periode Januari-Juni 2025 yang dipilih menggunakan teknik total sampling. Data dianalisis secara deskriptif dalam bentuk frekuensi dan persentase.
Hasil : Pasien hipertensi didominasi oleh perempuan (56,9%) dan kelompok usia 55-64 tahun (33,5%). Terapi obat antihipertensi yang paling banyak digunakan adalah terapi tunggal (56,5%), dengan golongan Calcium Channel Blocker (CCB), terutama Amlodipine (59,6%). Kombinasi dua obat yang paling sering digunakan adalah Candesartan dan Amlodipine (39,2%). Evaluasi terapi menunjukkan bahwa 87,6% penggunaan obat telah sesuai dengan rekomendasi JNC 8.
Kesimpulan : Penggunaan obat antihipertensi pada pasien rawat jalan di RSUD H.M. Ryacudu Kotabumi Lampung Utara didominasi oleh terapi tunggal dengan golongan CCB. Sebagian besar terapi yang diberikan telah sesuai dengan pedoman JNC 8 sehingga menunjukkan penerapan terapi obat antihipertensi yang umumnya telah mengikuti rekomendasi.
Kata Kunci : Hipertensi, Obat Antihipertensi, Pedoman JNC 8, Terapi Kombinasi, Terapi Tunggal.

ABSTRACT
Background: Hypertension is a non-communicable disease characterized by elevated blood pressure and is a leading cause of cardiovascular disease. The appropriate use of antihypertensive medication plays a crucial role in controlling blood pressure and preventing complications. This study aims to describe the use of antihypertensive drugs among outpatients at H.M. Ryacudu Regional General Hospital (RSUD) in Kotabumi, North Lampung, in 2025, and to evaluate the appropriateness of the therapy based on JNC 8 guidelines.
Methods: This study employed a non-experimental method with descriptive design. The study sample consisted of 499 medical records and prescriptions of hypertensive outpatients from the period of January to June 2025, selected using a total sampling technique. Data were analyzed descriptively in terms of frequencies and percentages.
Results: Hypertension patients were predominantly female (56.9%) and in the 55–64 age group (33.5%). Monotherapy was the most common antihypertensive treatment (56.5%), specifically using the calcium channel blocker (CCB) class—particularly Amlodipine (59.6%). The most frequently used two-drug combination was Candesartan and Amlodipine (39.2%). Therapy evaluation indicated that 87.6% of drug usage adhered to JNC 8 recommendations.
Conclusion: The use of antihypertensive medication among outpatients at H.M. Ryacudu Regional General Hospital in Kotabumi, North Lampung, is dominated by monotherapy using calcium channel blockers (CCBs). The majority of prescribed therapies align with JNC 8 guidelines, indicating that antihypertensive treatment practices generally adhere to recommendations.
Keywords: Antihypertensive Drugs, Combination Therapy, Hypertension, JNC 8 Guidelines, Monotherapy.

Item Type: Thesis (Diploma)
Uncontrolled Keywords: Hipertensi, Obat Antihipertensi, Pedoman JNC 8, Terapi Kombinasi, Terapi Tunggal.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Jurusan Farmasi > 48401-D3 Farmasi
Depositing User: Unnamed user with email D3farmasi
Date Deposited: 26 Aug 2026 06:36
Last Modified: 26 Aug 2026 06:36
URI: http://rama.poltekkespalembang.ac.id/id/eprint/4213

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