Analisis Faktor Karakteristik dengan Nilai Urea Reduction Ratio (URR) sebagai Indikator Hemodialisis Pasien GGK di RS Siti Khadijah Palembang

Latar belakang: Penyakit Gagal Ginjal Kronik (GGK) merupakan masalah kesehatan yang terus meningkat dan memerlukan terapi hemodialisis untuk mempertahankan fungsi tubuh. Keberhasilan hemodialisis dapat dievaluasi melalui Urea Reduction Ratio (URR) sebagai indikator adekuasi hemodialisis. Tujuan: Penelitian ini bertujuan menganalisis hubungan faktor karakteristik dengan nilai URR pada pasien GGK di RS Siti Khadijah Palembang. Metode: Penelitian analitik observasional dengan pendekatan cross sectional retrospektif menggunakan data rekam medis periode Mei 2025–Mei 2026. Sampel berjumlah 104 pasien yang dipilih secara purposive sampling. Analisis dilakukan secara univariat dan bivariat menggunakan uji Spearman (α=0,05). Hasil: Hasil menunjukkan mayoritas responden berusia lansia (51,9%) dan perempuan (53,8%). Rata-rata kadar ureum pre-hemodialisis 151,64 mg/dL dan post-hemodialisis 83,63 mg/dL. Analisis bivariat menunjukkan terdapat hubungan bermakna antara kadar ureum pre hemodialisis dan post hemodialisis dengan nilai URR (p<0,05), sedangkan usia dan jenis kelamin tidak menunjukkan hubungan bermakna (p>0,05). Hasil ini menunjukkan bahwa perubahan kadar ureum sebelum dan sesudah hemodialisis berperan dalam menentukan nilai URR sebagai indikator hemodialisis. Kesimpulan: Terdapat hubungan bermakna antara kadar ureum pre dan post-hemodialisis dengan nilai URR, sedangkan usia dan jenis kelamin tidak berhubungan bermakna. Disimpulkan bahwa kadar ureum pre dan post-hemodialisis berhubungan dengan nilai URR sebagai indikator adekuasi hemodialisis.

Background: Chronic Kidney Disease (CKD) is an increasing health problem requiring hemodialysis to maintain body function. Hemodialysis adequacy can be evaluated using the Urea Reduction Ratio (URR). Objetive: This study aimed to analyze the relationship between patient characteristics and URR among CKD patients at Siti Khadijah Hospital, Palembang. Methods: An observational analytic study with a retrospective cross-sectional design was conducted using medical records from May 2025 to May 2026. A total of 104 patients were selected through purposive sampling. Data were analyzed using univariate analysis and Spearman correlation (α=0.05). Results: Most participants were elderly (51.9%) and female (53.8%). The mean pre-hemodialysis urea level was 151.64 mg/dL and the post-hemodialysis level was 83.63 mg/dL. Bivariat analysis demonstrated significant relationships between pre hemodialysis and post hemodialysis blood urea levels and URR values (p<0,05). However, age and sex were not significantly associated with URR(p>0,05). These findings indicate that changes in blood urea levels before and after hemodialysis contribute to determining URR as an indicator of dialysis adequacy. Conclusions: Pre- and post-hemodialysis urea levels were significantly associated with URR, whereas age and sex were not. It is concluded that pre- and post-hemodialysis urea levels are associated with URR as an indicator of hemodialysis adequacy.