KORELASI NILAI HEMOGLOBIN A1C (HBA1C) DENGAN RED CELL DISTRIBUTION WIDTH (RDW) PADA PASIEN DIABETES MELITUS TIPE 2 DI RSUD PALEMBANG BARI

SADAMIYAH, RAHAYU (2026) KORELASI NILAI HEMOGLOBIN A1C (HBA1C) DENGAN RED CELL DISTRIBUTION WIDTH (RDW) PADA PASIEN DIABETES MELITUS TIPE 2 DI RSUD PALEMBANG BARI. Diploma thesis, POLTEKKES KEMENKES PALEMBANG.

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Abstract

Latar Belakang: Diabetes melitus tipe 2 (DMT2) merupakan penyakit metabolik kronis dengan prevalensi yang terus meningkat secara global maupun di Indonesia. Hemoglobin A1C (HbA1C) merupakan standar baku emas dalam memantau kontrol glikemik. Red Cell Distribution Width (RDW) merupakan parameter hematologi yang menggambarkan variasi ukuran sel darah merah yang diduga berkaitan dengan kondisi hiperglikemia. Tujuan: Mengetahui korelasi antara nilai HbA1C dengan RDW pada pasien diabetes melitus tipe 2 di RSUD Palembang BARI. Metode: Penelitian ini merupakan studi observasional analitik dengan desain cross sectional. Penelitian dilakukan di RSUD Palembang BARI pada 150 pasien DMT2 yang melakukan pemeriksaan HbA1C dan RDW dengan teknik total sampling. Data sekunder didapat dari rekam medis pada periode Desember 2025 hingga Mei 2026. Analisa data menggunakan uji normalitas Kolmogorov Smirnov dan uji korelasi Spearman. Hasil: Rata-rata nilai HbA1C pasien adalah 9,8374%, median 10,1550%, rentang 5,06-15,00% dan rata-rata nilai RDW adalah 13,146%, median 12,900% rentang 11,4-18,0%. Hasil uji korelasi Spearman menunjukkan koefisien korelasi (r) = -0,189 dengan p Value = 0,021 (p<0,05). Kesimpulan: Hasil penelitian menunjukkan terdapat korelasi negatif yang sangat lemah namun signifkan secara statistik antara nilai HbA1C dengan RDW pada pasien DM Tipe 2.

Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease with increasing prevalence globally and in Indonesia. Hemoglobin A1C (HbA1C) is the gold standard for monitoring glycemic control. Red Cell Distribution Width (RDW) is a hematological parameter that reflects red blood cell size variation, which is thought to be associated with hyperglycemic conditions. Objective: To determine the correlation between HbA1C and RDW values in type 2 diabetes mellitus patients at RSUD Palembang BARI. Methods: This was an analytical observational study with a cross sectional design. The study was conducted at RSUD Palembang BARI on 150 T2DM patients who underwent HbA1C and RDW examinations using total sampling technique. Secondary data were obtained from medical records during December 2025 to May 2026. Data analysis used the Kolmogorov Smirnov normality test and Spearman correlation test. Results: The mean of HbA1C value was 9.8374%, median 10.1550%, range 5.06-15.00% and the mean of RDW value was 13.146%, median 12.900%, range 11.3-18.0%. Spearman corelation test showed correlation coefficient (r) = -0.189 and p Value = 0.021 (p<0.05). Conclusion: There is a very weak but statistically significant negative correlation between HbA1C and RDW in T2DM patients.

Item Type: Thesis (Diploma)
Uncontrolled Keywords: DM, HbA1C, RDW
Subjects: R Medicine > R Medicine (General)
R Medicine > RB Pathology
Divisions: Jurusan Teknologi Laboratorium Medis > 13350-D4 Teknologi Laboratorium Medis
Depositing User: Unnamed user with email D4tlm
Date Deposited: 28 Jul 2026 03:51
Last Modified: 28 Jul 2026 03:51
URI: http://rama.poltekkespalembang.ac.id/id/eprint/3418

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